Oxidation of guanazyls (112) with nitric acid or preferably lead tetraacetate leads to tetrazole (113) with the elimination of urea. The reaction proceeds well, with near-quantitative yields, with a variety of 1- or 3- substituents as well as with bisguanazyls, e. g., 114 (Scheme 16).23-25,176
Oxidation of Guanazyls
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